Perflutren Lipid Microspheres Ultrasound in Diagnosing Patients with Intraocular Tumors Undergoing Diagnostic Surgery
20 Years and older, Male and Female
Summary
This clinical trial studies perflutren lipid microsphere ultrasound in diagnosing patients with intraocular (within the eye ball) tumors undergoing diagnostic surgery. Ultrasound is a procedure that uses high-energy sound waves to look at tissues and organs inside the body. Perflutren lipid microsphere is a contrast agent that helps doctors to see the blood vessels more clearly during ultrasound. Using perflutren lipid microsphere during intraocular ultrasound before eye surgery may help doctors see the blood vessels in and around the tumor and may help doctors determine whether the patient has melanoma or other intraocular tumors including retinal tumors.
Objectives
PRIMARY OBJECTIVES:
I. To show that it is possible to acoustically identify microbubbles in vascular channels in intraocular tumors, including uveal melanoma, metastases and retinal tumors.
OUTLINE:
Patients undergo routine ocular ultrasonography and then receive perflutren lipid microsphere intravenously (IV) during the scheduled intraocular ultrasonography.
Eligibility
- Adults with intraocular tumors (melanoma, metastasis, retinal tumors) who are going to undergo enucleation diagnosed in the Emory Eye Center Ocular Oncology Service; patients will be assessed by a cardiologist or cardiology fellows
Treatment Sites in Georgia
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