Neuroblastoma Biology Study
31 Days - 99 Years, Male and Female
Summary
Medical scientists want to find better ways to treat neuroblastoma and to find ways to
prevent the tumor from growing back. To do this, they need more information about the
characteristics of neuroblastoma cells. Therefore, they want to study samples of
neuroblastoma tissues and neuroblastoma and normal cells in the blood and bone marrow
that may be related to the growth of neuroblastoma cells. Doctors and other medical
scientists also want to find better ways to detect and measure neuroblastoma to improve
the ability to follow the response of tumor cells to therapy.
Objectives
The purposes of this study are:
To establish a storage place or bank of samples of blood, bone marrow, and/or tumor, and
molecular components isolated from these samples from children with neuroblastoma. The
stored specimens will be shared with laboratory researchers studying high risk
neuroblastoma.
To collect clinical data (such as treatments received, date of diagnosis, tumor stage,
etc) and radiology scans to provide this information as needed for the laboratory studies
to be done on the specimens.
To obtain neuroblastoma tumor cells from tumor tissue, bone marrow, and/or blood to use
to start cell lines, or tumor cells that will keep growing in the laboratory. These cell
lines will be shared with laboratory researchers studying high risk neuroblastoma.
Eligibility
- Patients must be greater than or 31 days of age.
- Patients must have had a diagnosis of high risk neuroblastoma either by histological verification of neuroblastoma and/or demonstration of tumor cells in the bone marrow with increased urinary catecholamines.
- All patients with refractory or recurrent high risk neuroblastoma at NANT institutions are eligible regardless of disease status (including no measurable or evaluable tumor) as long as they undergo a disease evaluation and appropriate samples are submitted.
- Additionally, all patients with high risk neuroblastoma without relapse treated at a NANT institution are eligible if undergoing a disease evaluation, as long as Children's Oncology Group specimens are prioritized.
Treatment Sites in Georgia
1405 Clifton Road NE
3rd Floor
Atlanta, GA 30322
404-785-0853
www.choa.org
**Clinical trials are research studies that involve people. These studies test new ways to prevent, detect, diagnose, or treat diseases. People who take part in cancer clinical trials have an opportunity to contribute to scientists’ knowledge about cancer and to help in the development of improved cancer treatments. They also receive state-of-the-art care from cancer experts...
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