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Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation


Active: Yes
Cancer Type: Colon/Rectal Cancer
Unknown Primary
NCT ID: NCT06252649
Trial Phases: Phase III Protocol IDs: 20210081 (primary)
NCI-2024-03471
Eligibility: 18 Years and older, Male and Female Study Type: Treatment
Study Sponsor: Amgen, Inc.
NCI Full Details: http://clinicaltrials.gov/show/NCT06252649

Summary

The aim of this study is to compare progression free survival (PFS) in treatment-naïve
Participants with KRAS p.G12C mutated metastatic colorectal cancer (mCRC) receiving
sotorasib, panitumumab and FOLFIRI vs FOLFIRI with or without bevacizumab-awwb.

Treatment Sites in Georgia

Northside Hospital Cancer Institute
1000 Johnson Ferry Road NE
Atlanta, GA 30342
404-303-3355
www.northside.com

**Clinical trials are research studies that involve people. These studies test new ways to prevent, detect, diagnose, or treat diseases. People who take part in cancer clinical trials have an opportunity to contribute to scientists’ knowledge about cancer and to help in the development of improved cancer treatments. They also receive state-of-the-art care from cancer experts... Click here to learn more about clinical trials.