Phase II Trial Evaluating the Efficacy and Safety of Sargramostim Post-Infusion of T-Replete HLA Mismatched Peripheral Blood Haploidentical Hematopoietic Stem Cells and With Post Transplant Cyclophosphamide

Active:	Yes
Cancer Type:	Hematopoietic Malignancies	NCT ID:	NCT04237623
Trial Phases:	Phase II	Protocol IDs:	NSH 1246 (primary)
Eligibility:	, Male and Female	Study Type:
Study Sponsor:	Northside Hospital, Inc.
NCI Full Details:	https://clinicaltrials.gov/study/NCT04237623

Summary

Given the increased number of HLA-mismatched haploidentical transplantation with post-transplant cyclophosphamide performed each year and the high risk of infectious complications associated with this type of transplant, the investigators suggest that GM-CSF administration post-infusion of T-replete haploidentical stem cells and post-transplant cyclophosphamide can yield similar count recovery rates to G-CSF with a potential of lowering risk of infectious complications.

Treatment Sites in Georgia

Northside Hospital Cancer Institute - Bone Marrow Transplant (BMT)
1000 Johnson Ferry Road NE
Atlanta, GA 30342
404-851-8523

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