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DAREON??-8: A Study to Test How Well Different Doses of BI 764532 in Addition to Standard of Care Are Tolerated by People With Advanced Small Cell Lung Cancer


Active: Yes
Cancer Type: Lung Cancer NCT ID: NCT06077500
Trial Phases: Phase I Protocol IDs: 1438-0008 (primary)
NCI-2024-04226
Eligibility: 18 Years and older, Male and Female Study Type: Treatment
Study Sponsor: Boehringer Ingelheim Pharmaceuticals Inc
NCI Full Details: http://clinicaltrials.gov/show/NCT06077500

Summary

This study is open to adults with extensive stage small cell lung cancer. The study is in
people with advanced cancer that are eligible for standard of care including chemotherapy
and anti-PD-L1 (Programmed Cell Death Ligand 1) immunotherapy.

The purpose of this study is to find out the highest dose of BI 764532 that people can
tolerate when taken together with standard of care. BI 764532 is an antibody-like
molecule that may help the immune system fight cancer. Participants get BI 764532 and
different standard treatments as infusions into a vein.

If there is benefit for the participants and if they can tolerate it, the treatment is
given for the entire duration of the study. During this time, participants visit the
study site regularly. The visits also depend on the response to the treatment. At the
study visits, the doctors check the health of the participants, take necessary laboratory
tests, and note any health problems that could have been caused by the study treatment.

Treatment Sites in Georgia

Winship Cancer Institute of Emory University
1365 Clifton Road NE
Building C
Atlanta, GA 30322
winshipcancer.emory.edu

**Clinical trials are research studies that involve people. These studies test new ways to prevent, detect, diagnose, or treat diseases. People who take part in cancer clinical trials have an opportunity to contribute to scientists’ knowledge about cancer and to help in the development of improved cancer treatments. They also receive state-of-the-art care from cancer experts... Click here to learn more about clinical trials.