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ACE1831 in Adult Subjects With Relapsed/ Refractory CD20-expressing B-cell Malignancies


Active: Yes
Cancer Type: Hematopoietic Malignancies
Lymphoma
Non-Hodgkin Lymphoma
Unknown Primary
NCT ID: NCT05653271
Trial Phases: Phase I Protocol IDs: ACE1831-001 (primary)
NCI-2023-03335
Eligibility: 18 Years and older, Male and Female Study Type: Treatment
Study Sponsor: Acepodia Biotech, Inc.
NCI Full Details: http://clinicaltrials.gov/show/NCT05653271

Summary

ACE1831 is an off-the-shelf, allogeneic gamma delta T (gdT) cell therapy derived from
healthy donors, that is under investigation for the treatment of CD20-expressing B-cell
malignancies.

The ACE1831-001 study is an open-label, Phase I, first-in-human (FIH) study that aims to
evaluate the safety and tolerability, pharmacokinetics and pharmacodynamics, and efficacy
of ACE1831 in patients with CD20-expressing Non-Hodgkin lymphoma.

Treatment Sites in Georgia

Winship Cancer Institute of Emory University
1365 Clifton Road NE
Building C
Atlanta, GA 30322
winshipcancer.emory.edu

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