Biospecimen Collection in Identifying Genetic Changes in Patients with Breast, Prostate, Colorectal, Liver, or Kidney Cancer or Multiple Myeloma Undergoing Surgery

Active:	Yes
Cancer Type:	Breast Cancer Colon/Rectal Cancer Kidney Cancer Liver Cancer / Hepatoblastoma Multiple Myeloma Plasma cell neoplasm Prostate Cancer Solid Tumor Unknown Primary	NCT ID:	NCT04955808
Trial Phases:		Protocol IDs:	DCP-002 (primary) DCP-002 DCP-002 NCI-2017-01572
Eligibility:	18 Years and older, Male and Female	Study Type:	Other
Study Sponsor:	National Cancer Institute Division of Cancer Prevention
NCI Full Details:	http://clinicaltrials.gov/show/NCT04955808

Summary

This research trial studies how well biospecimen collection works in identifying genetic changes in patients with breast, prostate, colorectal, liver, or kidney cancer or multiple myeloma undergoing surgery. Studying samples collected during surgery may add to the understanding of cancer by looking for the genetic changes that cause early cancer onset in people of certain racial and ethnic groups.

Objectives

PRIMARY OBJECTIVE:
I. To acquire tissue and blood, and other biospecimens for research purposes during procedures for clinical care to accelerate our understanding of the molecular basis of early onset cancers occurring in racial and/or ethnic minority populations through the application of genome analysis technologies, including large- scale genome sequencing and clinical data analysis.

OUTLINE:
Patients undergo collection of tumor tissue during surgery. Patients also undergo blood samples. Samples collected may undergo genetic analysis including whole exome sequencing.

After completion of study, patients are followed for up at 6 and 12 months.

**Clinical trials are research studies that involve people. These studies test new ways to prevent, detect, diagnose, or treat diseases. People who take part in cancer clinical trials have an opportunity to contribute to scientists’ knowledge about cancer and to help in the development of improved cancer treatments. They also receive state-of-the-art care from cancer experts... Click here to learn more about clinical trials.