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TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer


Active: Yes
Cancer Type: Multiple Myeloma
Non-Hodgkin Lymphoma
Plasma cell neoplasm
NCT ID: NCT02693535
Trial Phases: Phase II Protocol IDs: Pro00014171 (primary)
NCI-2017-00510
Eligibility: 12 Years and older, Male and Female Study Type: Treatment
Study Sponsor: American Society of Clinical Oncology
NCI Full Details: http://clinicaltrials.gov/show/NCT02693535

Summary

The purpose of the study is to learn from the real world practice of prescribing targeted
therapies to patients with advanced cancer whose tumor harbors a genomic variant known to
be a drug target or to predict sensitivity to a drug.

NOTE: Due to character limits, the arms section does NOT include all TAPUR Study relevant
biomarkers. For additional information, contact TAPUR@asco.org, or if a patient, your
nearest participating TAPUR site (see participating centers).

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Results in publication or poster presentation format are posted as they become available
for individual cohorts at www.tapur.org/news. The results may be accessed at any time.
All results will be made available on clinicaltrials.gov at the end of the study.
Indexing of available results on PubMed is in progress.

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Objectives

The Targeted Agent and Profiling Utilization Registry (TAPUR) Study is a non-randomized
clinical trial that aims to describe the safety and efficacy of commercially available,
targeted anticancer drugs prescribed for treatment of patients with advanced cancer that
has a potentially actionable genomic variant. TAPUR will study Food and Drug
Administration (FDA)-approved targeted therapies that are contributed by collaborating
pharmaceutical companies, catalogue the choice of molecular profiling test by clinical
oncologists and develop hypotheses for additional clinical trials.

Treatment Sites in Georgia

City of Hope Atlanta
600 Celebrate Life Parkway
Newnan, GA 30265
770-400-6169
www.cityofhope.org/locations/atlanta/atlanta-cancer-center



Nancy N. and J.C. Lewis Cancer Research Pavilion at St. Joseph Candler
225 Candler Drive
Savannah, GA 31405
912-819-5778
www.sjchs.org



Winship Cancer Institute of Emory University
1365 Clifton Road NE
Building C
Atlanta, GA 30322
winshipcancer.emory.edu

**Clinical trials are research studies that involve people. These studies test new ways to prevent, detect, diagnose, or treat diseases. People who take part in cancer clinical trials have an opportunity to contribute to scientists’ knowledge about cancer and to help in the development of improved cancer treatments. They also receive state-of-the-art care from cancer experts... Click here to learn more about clinical trials.